Nrf2 links epidermal barrier function with antioxidant defense
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چکیده
منابع مشابه
Nrf2 links epidermal barrier function with antioxidant defense
The skin provides an efficient permeability barrier and protects from microbial invasion and oxidative stress. Here, we show that these essential functions are linked through the Nrf2 transcription factor. To test the hypothesis that activation of Nrf2 provides skin protection under stress conditions, we determined the consequences of pharmacological or genetic activation of Nrf2 in keratinocyt...
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ژورنال
عنوان ژورنال: EMBO Molecular Medicine
سال: 2012
ISSN: 1757-4676,1757-4684
DOI: 10.1002/emmm.201200219